Xurography Actuated Valving for Arbitrary Timing of Centrifugal Flow Control in Parallelized Multi-step Bioassays
نویسندگان
چکیده
Here we introduce a new, instrument controlled valving scheme for the centrifugal platform which is based upon dissolvable film (DF) technology. Liquid, restrained at any point upon the disc, is prevented from wetting a DF via a trapped gas pocket. From this pocket a pneumatic channel runs to a sealed vent located on the top surface of the disc. Controlled scouring of this seal by a robotic knifecutter permits venting of the trapped gas, and thus actuation of the valve. To demonstrate the potential of these valves, we present a disc developed towards a biplex liver assay panel.
منابع مشابه
Event-triggered logical flow control for comprehensive process integration of multi-step assays on centrifugal microfluidic platforms.
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